Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CD38 | P28907 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428436 | 1.00 | MAOB (0.43) | MAOBRAB9AALDH1A1LMNACNR2 | |
| SCHEMBL31428996 | 0.88 | MAOB (0.42) | MAOBRAB9AALDH1A1LMNACNR2 | |
| SCHEMBL31428913 | 0.82 | HPGD (0.43) | MAOBRAB9AALDH1A1NPC1 | |
| SCHEMBL31428611 | 0.72 | HRH3 (0.47) | LMNAMCHR1CD38CCR3KCNH2 | |
| SCHEMBL30163508 | 0.71 | RAB9A (0.57) | MAOBRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL30163534 | 0.70 | L3MBTL3 (0.47) | RAB9ANPC1 | |
| SCHEMBL31429046 | 0.69 | GPR183 (0.42) | MAOBRAB9AALDH1A1LMNANPC1 | |
| SCHEMBL24977246 | 0.69 | GPR183 (0.41) | MAOBRAB9AALDH1A1KCNH2NPC1 | |
| SCHEMBL30163574 | 0.68 | HRH3 (0.42) | RAB9ALMNAKCNH2NPC1SMN1; SMN2 | |
| SCHEMBL13410163 | 0.65 | CYP1A2 (0.61) | RAB9AALDH1A1LMNANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |