Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428796 | 1.00 | REN (0.33) | RENCYP3A4KCNH2NR1H4UBE2M | |
| SCHEMBL31428883 | 0.90 | MMP9 (0.36) | RENCYP3A4KCNH2NR1H4UBE2M | |
| SCHEMBL31428558 | 0.87 | GRM2 (0.35) | KCNH2NR1H4HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL24975810 | 0.87 | GRM2 (0.35) | KCNH2NR1H4HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL31428765 | 0.86 | ALDH1A1 (0.32) | NR1H4UBE2MDCUN1D1 | |
| SCHEMBL24975804 | 0.85 | GRM2 (0.35) | CYP3A4NR1H4HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL31428746 | 0.85 | GRM2 (0.35) | CYP3A4NR1H4HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL31428465 | 0.85 | GRM2 (0.39) | KCNH2NR1H4HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL24975808 | 0.84 | SLC6A2 (0.39) | KCNH2NR1H4HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL31428539 | 0.82 | GRM2 (0.35) | NR1H4GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |