Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GUSB | P08236 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428983 | 0.92 | ALDH1A1 (0.49) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL31428714 | 0.89 | IP6K1 (0.48) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL24976057 | 0.89 | IP6K1 (0.48) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL31428599 | 0.85 | NPC1 (0.55) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL31428875 | 0.84 | ABCG2 (0.49) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL31428992 | 0.82 | IP6K1 (0.53) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL31428616 | 0.81 | MAPT (0.60) | ALDH1A1MEN1KMT2ANPC1MAPT | |
| SCHEMBL31428537 | 0.80 | PDCD1 (0.52) | KDM4EALDH1A1MAPTLMNATP53 | |
| SCHEMBL30163537 | 0.80 | TLR9 (0.50) | ALDH1A1MAPT | |
| SCHEMBL24975611 | 0.77 | IP6K1 (0.55) | KDM4EALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |