Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 5/20 | 0.53 |
| ▸ | IP6K3 | Q96PC2 | 5/20 | 0.53 |
| ▸ | IP6K2 | Q9UHH9 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31429025 | 0.92 | IP6K1 (0.55) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL24975611 | 0.92 | IP6K1 (0.55) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL31428983 | 0.90 | ALDH1A1 (0.49) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL31428985 | 0.88 | CTRC (0.50) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL24976116 | 0.88 | CTRC (0.50) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL4059859 | 0.85 | MAPT (0.49) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL24975803 | 0.84 | NPC1 (0.56) | ALDH1A1KDM4ENPC1GAARAB9A | |
| SCHEMBL31428675 | 0.84 | NPC1 (0.56) | ALDH1A1KDM4ENPC1GAARAB9A | |
| SCHEMBL24975485 | 0.83 | ABCG2 (0.47) | ALDH1A1KDM4ENPC1GAATP53 | |
| SCHEMBL31428518 | 0.83 | ABCG2 (0.47) | ALDH1A1KDM4ENPC1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | IP6K1 1834/4885IP6K3 2089/4885IP6K2 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.