Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31429000 | 1.00 | TP53 (0.46) | TP53ABCG2ABCB1KDM4EMAPT | |
| SCHEMBL31428875 | 0.87 | ABCG2 (0.49) | TP53ABCG2ABCB1KDM4EMAPT | |
| SCHEMBL31428634 | 0.86 | ABCG2 (0.43) | TP53ABCG2ABCB1KDM4EMAPT | |
| SCHEMBL24975470 | 0.86 | ABCG2 (0.43) | TP53ABCG2ABCB1KDM4EMAPT | |
| SCHEMBL31428860 | 0.85 | MEN1 (0.53) | TP53KDM4EMAPTNPC1GAA | |
| SCHEMBL24975647 | 0.85 | MEN1 (0.53) | TP53KDM4EMAPTNPC1GAA | |
| SCHEMBL31428520 | 0.85 | MMP9 (0.48) | TP53ABCG2ABCB1KDM4EMAPT | |
| SCHEMBL24975610 | 0.84 | NPC1 (0.48) | TP53KDM4EMAPTNPC1GUSB | |
| SCHEMBL31428836 | 0.84 | NPC1 (0.48) | TP53KDM4EMAPTNPC1GUSB | |
| SCHEMBL24976143 | 0.84 | ABCG2 (0.46) | TP53ABCG2ABCB1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |