Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975470 | 1.00 | ABCG2 (0.43) | ABCG2ABCB1SLC7A5PPARGPPARA | |
| SCHEMBL24977054 | 0.88 | ABCG2 (0.47) | ABCG2ABCB1SLC7A5HDAC8MEN1 | |
| SCHEMBL31428706 | 0.88 | ABCG2 (0.47) | ABCG2ABCB1SLC7A5HDAC8MEN1 | |
| SCHEMBL31428735 | 0.86 | ALOX15 (0.39) | ABCG2ABCB1SLC7A5HDAC8MEN1 | |
| SCHEMBL24975471 | 0.86 | ALOX15 (0.39) | ABCG2ABCB1SLC7A5HDAC8MEN1 | |
| SCHEMBL24976140 | 0.86 | TP53 (0.46) | ABCG2ABCB1SLC7A5PPARGPPARA | |
| SCHEMBL31429000 | 0.86 | TP53 (0.46) | ABCG2ABCB1SLC7A5PPARGPPARA | |
| SCHEMBL24975481 | 0.85 | ABCG2 (0.43) | ABCG2ABCB1SLC7A5MEN1KMT2A | |
| SCHEMBL31428970 | 0.85 | ABCG2 (0.43) | ABCG2ABCB1SLC7A5MEN1KMT2A | |
| SCHEMBL24975467 | 0.85 | ABCG2 (0.45) | ABCG2ABCB1SLC7A5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | ABCG2 334/4885ABCB1 665/4885SLC7A5 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.