SCHEMBL2497618

SCHEMBL2497618

CC(C)(C)c1cccc(O)c1-c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
TSHR P16473 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
CA2 P00918 1/20 0.50
GABRA1 P14867 1/20 0.44
GABRB2 P47870 1/20 0.44
PDE4A P27815 2/20 0.41
PDE4B Q07343 2/20 0.41
PDE4C Q08493 2/20 0.41
PDE4D Q08499 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 2/20 0.40
HPGD P15428 1/20 0.40
BCL2L1 Q07817 1/20 0.40
PTPN5 P54829 1/20 0.40
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
HDAC4 P56524 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC8 Q9BY41 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27496943 0.93 ALDH1A1 (0.52) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL28607701 0.89 ALDH1A1 (0.52) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL10614412 0.88 ALDH1A1 (0.48) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL28563622 0.85 ALDH1A1 (0.52) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL29888677 0.85 ALDH1A1 (0.65) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL29169320 0.85 ALDH1A1 (0.65) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL16505950 0.85 CNR1 (0.51) ALDH1A1TSHRTDP1CA2PDE4A
SCHEMBL7702950 0.84 ALDH1A1 (0.48) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL27908556 0.81 CA2 (0.44) ALDH1A1TSHRTDP1CA2GABRA1
Bicarbonate SCHEMBL2538486 0.80 CNR2 (0.48) ALDH1A1TSHRTDP1PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2789640-B1 POLYCARBONATE RESINS, POLYCARBONATE RESIN COMPOSITIONS, OPTICAL FILM, AND POLYCARBONATE RESIN MOLDED ARTICLES MITSUBISHI CHEM CORP (JP) 2019-01-02 EP disclosed
CN-105246940-B Optical semiconductor sealing solidification compound 株式会社大赛璐 2018-09-04 CN disclosed
US-9685597-B2 Curable composition for sealing optical semiconductor DAICEL CORPORATION (JP) 2017-06-20 US disclosed
US-20160126431-A1 CURABLE COMPOSITION FOR SEALING OPTICAL SEMICONDUCTOR DAICEL CORPORATION (JP) 2016-05-05 US disclosed
EP-3006481-A1 CURABLE COMPOSITION FOR SEALING OPTICAL SEMICONDUCTOR Daicel Corporation (JP) 2016-04-13 EP disclosed
EP-2789640-A1 Polycarbonate resins, polycarbonate resin compositions, optical film, and polycarbonate resin molded articles MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-15 EP disclosed
EP-2371877-A1 POLYCARBONATE RESIN, POLYCARBONATE RESIN COMPOSITION, OPTICAL FILM, AND POLYCARBONATE RESIN MOLDED ARTICLE Mitsubishi Chemical Corporation (JP) 2011-10-05 EP disclosed
EP-0368459-B1 Coating compositions ICI PLC (GB) 1995-12-27 EP disclosed
EP-0200397-B1 AMINE-EPOXIDE REACTION PRODUCTS AND AQUEOUS DISPERSIONS THEREOF USEFUL IN COATING COMPOSITIONS SUITABLE FOR ELECTRODEPOSITION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-02-26 EP disclosed
US-5057556-A COATING COMPOSITIONS COMPRISING NON-GELLED AMINE-EPOXIDE REACTION PRODUCTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-15 US disclosed
EP-0368459-A1 Coating compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-05-16 EP disclosed
EP-0200397-A2 Amine-epoxide reaction products and aqueous dispersions thereof useful in coating compositions suitable for electrodeposition IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-11-05 EP disclosed