Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688382 | 0.84 | ALDH1A1 (0.61) | ALDH1A1CA1CA2CA9CYP3A4 | |
| SCHEMBL9100593 | 0.81 | ALDH1A1 (0.67) | ALDH1A1CA1CA2CA9CYP3A4 | |
| SCHEMBL27968563 | 0.79 | ALDH1A1 (0.54) | ALDH1A1RECQLTDP1CA1CA2 | |
| SCHEMBL863475 | 0.78 | ALDH1A1 (0.73) | ALDH1A1CA1CA2CA9CYP3A4 | |
| SCHEMBL20194327 | 0.77 | ALDH1A1 (0.53) | ALDH1A1RECQLTDP1CA1CA2 | |
| SCHEMBL4970386 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TDP1CA1CA2CA9 | |
| SCHEMBL8861453 | 0.74 | ALDH1A1 (0.62) | ALDH1A1RECQLCA1CA2CA9 | |
| SCHEMBL6201233 | 0.73 | ALDH1A1 (0.51) | ALDH1A1CA1CA2CA9AR | |
| SCHEMBL9764610 | 0.71 | ALDH1A1 (0.58) | ALDH1A1CA1CA2CA9KDM4E | |
| SCHEMBL28419877 | 0.71 | ALDH1A1 (0.57) | ALDH1A1TDP1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4378933-A1 | USE OF 3-ARYLPHTHALIDES AND DERIVATIVES THEREOF AS ANTI-INFLAMMATORY AGENTS | Universidad de Cádiz (ES) | 2024-06-05 | — | — | EP | disclosed |
| WO-2023007042-A1 | USE OF 3-ARYLPHTHALIDES AND DERIVATIVES THEREOF AS ANTI-INFLAMMATORY AGENTS | UNIVERSIDAD DE CÁDIZ (ES) | 2023-02-02 | — | — | WO | disclosed |