Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863475 | 0.81 | ALDH1A1 (0.73) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL247073 | 0.81 | ALDH1A1 (1.00) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL11547373 | 0.81 | ALDH1A1 (0.67) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL28345186 | 0.81 | ALDH1A1 (0.67) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL24976244 | 0.81 | ALDH1A1 (0.53) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL8861453 | 0.81 | ALDH1A1 (0.62) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL28419877 | 0.80 | ALDH1A1 (0.57) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL11540712 | 0.77 | ALDH1A1 (0.61) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL11550909 | 0.77 | ALDH1A1 (0.61) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL6201233 | 0.77 | ALDH1A1 (0.51) | ALDH1A1GAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996021662-A1 | THE USE OF HETEROCYCLIC COMPOUNDS AS ANTIOXIDANTS, RADICAL SCAVENGERS, Fe2+ COMPLEXING AGENTS, TISSUE- AND/OR NEUROPROTECTANTS | RISE FRODE (NO) | 1996-07-18 | — | — | WO | disclosed |