SCHEMBL2497655

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1170484	0.89	LMNA (1.00)	LMNASMN1; SMN2TSHRHTTSLC5A2
	SCHEMBL2496126	0.85	CXCR3 (0.77)	LMNASMN1; SMN2TSHRCXCR3HTT
	SCHEMBL5460666	0.83	MAPT (0.69)	LMNASMN1; SMN2TSHRCXCR3HTT
	SCHEMBL2493570	0.83	LMNA (0.54)	LMNASMN1; SMN2TSHRCXCR3HTT
	SCHEMBL3207909	0.83	TP53 (0.68)	LMNASMN1; SMN2TSHRCXCR3HTT
	SCHEMBL2495808	0.82	MAPT (0.61)	LMNASMN1; SMN2TSHRCXCR3HTT
	SCHEMBL2493856	0.82	MAPT (0.64)	LMNASMN1; SMN2TSHRCXCR3HTT
	SCHEMBL3205881	0.81	TP53 (0.74)	LMNASMN1; SMN2TSHRCXCR3HTT
	SCHEMBL1170639	0.79	SLC5A2 (0.78)	LMNASMN1; SMN2TSHRCXCR3HTT
	SCHEMBL2475227	0.79	LMNA (0.79)	LMNASMN1; SMN2TSHRHTTSLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.