Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 0.55 |
| ▸ | PRKG1 | Q13976 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2501551 | 0.90 | ROCK2 (0.69) | ROCK2PRKG1 | |
| SCHEMBL2474241 | 0.88 | ROCK2 (0.46) | ROCK2PRKG1MAPTACACBCNR1 | |
| SCHEMBL2500299 | 0.87 | ROCK2 (0.49) | ROCK2PRKG1CNR2 | |
| SCHEMBL2477830 | 0.87 | ROCK2 (0.51) | ROCK2PRKG1 | |
| SCHEMBL18281087 | 0.87 | ROCK2 (0.51) | ROCK2PRKG1 | |
| SCHEMBL2479130 | 0.87 | ROCK2 (0.51) | ROCK2PRKG1 | |
| SCHEMBL2479913 | 0.86 | ROCK2 (0.58) | ROCK2PRKG1ACACBCNR1MMP1 | |
| SCHEMBL2474149 | 0.80 | GLA (0.53) | MEN1CYP3A4KMT2A | |
| SCHEMBL2480794 | 0.78 | ROCK2 (0.42) | ROCK2PRKG1MAPTCNR2 | |
| SCHEMBL13504492 | 0.78 | ROCK2 (0.42) | ROCK2PRKG1MAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373620-A1 | NOVEL 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-10-12 | — | — | EP | disclosed |