Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.49 |
| ▸ | KIT | P10721 | 9/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474241 | 0.90 | ROCK2 (0.46) | ROCK2PRKG1KITCNR2 | |
| SCHEMBL2479130 | 0.89 | ROCK2 (0.51) | ROCK2PRKG1 | |
| SCHEMBL2477830 | 0.89 | ROCK2 (0.51) | ROCK2PRKG1 | |
| SCHEMBL18281087 | 0.89 | ROCK2 (0.51) | ROCK2PRKG1 | |
| SCHEMBL2497697 | 0.87 | ROCK2 (0.55) | ROCK2PRKG1CNR2 | |
| SCHEMBL2480794 | 0.85 | ROCK2 (0.42) | ROCK2PRKG1KITCNR2 | |
| SCHEMBL13504286 | 0.85 | ROCK2 (0.42) | ROCK2PRKG1KITCNR2 | |
| SCHEMBL13504492 | 0.85 | ROCK2 (0.42) | ROCK2PRKG1KITCNR2 | |
| SCHEMBL16564468 | 0.84 | BCHE (0.40) | ROCK2PRKG1 | |
| SCHEMBL27977456 | 0.83 | ROCK2 (0.40) | ROCK2PRKG1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2907804-A1 | Novel 4-(azacycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof in human medicine and in cosmetics | Galderma Research & Development (FR) | 2015-08-19 | — | — | EP | claimed |
| EP-2907804-A1 | Novel 4-(azacycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof in human medicine and in cosmetics | Galderma Research & Development (FR) | 2015-08-19 | — | — | EP | disclosed |
| EP-2373620-A1 | NOVEL 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-10-12 | — | — | EP | disclosed |