Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.54 |
| ▸ | FAAH | O00519 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21348323 | 0.93 | MGLL (0.59) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL6753848 | 0.89 | MGLL (0.55) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL7096979 | 0.85 | MGLL (0.58) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL24978398 | 0.83 | MGLL (0.56) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL8088363 | 0.81 | MGLL (0.54) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL28633544 | 0.81 | MGLL (0.54) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL8888140 | 0.80 | MGLL (0.52) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL6534708 | 0.80 | MGLL (0.42) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL5361313 | 0.79 | MGLL (0.61) | MGLLFAAHALDH1A1HPGDHSP90AA1 | |
| SCHEMBL24978575 | 0.79 | MGLL (0.50) | MGLLFAAHALDH1A1HPGDHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226313-A1 | CEACAM5 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | SEAGEN INC. | 2024-07-11 | — | — | US | disclosed |
| US-20240226313-A1 | CEACAM5 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | SEAGEN INC. | 2024-07-11 | — | — | US | disclosed |
| US-20230036256-A1 | CAMPTOTHECIN CONJUGATES | SEAGEN INC. | 2023-02-02 | — | — | US | disclosed |
| CN-115636863-A | Dexamethasone derivative containing maleimide segment and preparation method thereof | 中国医学科学院医药生物技术研究所 | 2023-01-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226313-A1 | CEACAM5 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | EPCAM, TOP2A, SPAG5 | MGLL 4028/4885FAAH 3433/4885ALDH1A1 388/4885 |
| US-20230036256-A1 | CAMPTOTHECIN CONJUGATES | DCLRE1A, TOP2A, PAICS | MGLL 4556/4885FAAH 4082/4885ALDH1A1 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.