SCHEMBL24980873

SCHEMBL24980873

COC1C(n2cc(-c3csc(N)n3)nn2)[C@@H](OC(C)=O)C(COC(C)=O)O[C@@H]1Sc1ccc(C#N)c(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LGALS1 P09382 10/20 0.61
LGALS3 P17931 13/20 0.48
LGALS9 O00182 2/20 0.47
LGALS8 O00214 2/20 0.47
LGALS4 P56470 2/20 0.47
LGALS7; LGALS7B P47929 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29661706 1.00 LGALS1 (0.61) LGALS1LGALS3LGALS9LGALS8LGALS4
SCHEMBL24980874 1.00 LGALS1 (0.61) LGALS1LGALS3LGALS9LGALS8LGALS4
SCHEMBL29661738 0.87 LGALS3 (0.45) LGALS1LGALS3LGALS9LGALS8LGALS4
SCHEMBL21189793 0.85 LGALS3 (0.65) LGALS1LGALS3LGALS9LGALS8LGALS4
SCHEMBL21189791 0.85 LGALS3 (0.65) LGALS1LGALS3LGALS9LGALS8LGALS4
SCHEMBL24981303 0.85 LGALS1 (0.84) LGALS1LGALS3LGALS9LGALS8LGALS4
SCHEMBL24980726 0.85 LGALS1 (0.84) LGALS1LGALS3LGALS9LGALS8LGALS4
SCHEMBL29661539 0.85 LGALS1 (0.84) LGALS1LGALS3LGALS9LGALS8LGALS4
SCHEMBL22865325 0.85 LGALS1 (0.65) LGALS1LGALS3LGALS9LGALS8LGALS4
SCHEMBL24980651 0.85 LGALS1 (0.65) LGALS1LGALS3LGALS9LGALS8LGALS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230014870-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230014870-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS LGALS1, LGALS3, LGALS2 LGALS1 1/4885LGALS3 2/4885LGALS9 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.