Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116405 | 0.85 | CNR1 (0.35) | CNR1TRPA1ATMCHEK1WEE1 | |
| SCHEMBL13651415 | 0.80 | CYP1A1 (0.38) | CNR1TRPA1ATMCHEK1WEE1 | |
| SCHEMBL30834716 | 0.79 | TRPA1 (0.52) | CNR1TRPA1ATMNUDT1CNR2 | |
| SCHEMBL218508 | 0.79 | TRPA1 (0.52) | CNR1TRPA1ATMNUDT1CNR2 | |
| Ammonia Solution, Strong SCHEMBL15862222 | 0.77 | TRPA1 (0.50) | CNR1TRPA1ATMNUDT1CNR2 | |
| Ammonia Solution, Strong SCHEMBL22444763 | 0.77 | TRPA1 (0.50) | CNR1TRPA1ATMNUDT1CNR2 | |
| Hydrogen Sulfide SCHEMBL1538405 | 0.77 | TRPA1 (0.50) | CNR1TRPA1ATMNUDT1CNR2 | |
| SCHEMBL28434186 | 0.76 | ESR2 (0.49) | CNR1ALDH1A1GAACYP1A2 | |
| SCHEMBL23198745 | 0.76 | TRPA1 (0.41) | CNR1TRPA1ATMNUDT1CNR2 | |
| SCHEMBL19838629 | 0.74 | TRPA1 (0.48) | CNR1TRPA1ATMNUDT1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4122537-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | Gilead Sciences, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |