Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16156903 | 0.88 | PTGS1 (0.53) | NOD1PTGS1PTGS2FOLH1 | |
| SCHEMBL22388827 | 0.85 | NOD1 (0.57) | NOD1PTGS1PTGS2 | |
| SCHEMBL25130460 | 0.84 | PTGS1 (0.46) | NOD1PTGS1PTGS2NPSR1ALDH1A1 | |
| SCHEMBL22311921 | 0.83 | PTGS1 (0.61) | NOD1PTGS1PTGS2NPSR1FOLH1 | |
| SCHEMBL22863839 | 0.83 | HPGD (0.49) | NOD1FOLH1MEN1KMT2AALDH1A1 | |
| SCHEMBL13351414 | 0.82 | PTGS1 (0.50) | NOD1PTGS1PTGS2NPSR1ALDH1A1 | |
| SCHEMBL17721377 | 0.82 | PTGS1 (0.58) | PTGS1PTGS2NPSR1KDM4EMEN1 | |
| SCHEMBL31235812 | 0.82 | AKT1 (0.42) | NOD1PTGS1PTGS2FOLH1KMT2A | |
| SCHEMBL7996266 | 0.82 | SLC6A5 (0.50) | NOD1MMP2MMP9PTGS1PTGS2 | |
| SCHEMBL23736436 | 0.82 | PTGS1 (0.44) | NOD1PTGS1PTGS2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025327-A1 | CONJUGATES OF TUBULYSIN DERIVATIVES AND CELL BINDING MOLECULES AND METHODS OF MAKING | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025327-A1 | CONJUGATES OF TUBULYSIN DERIVATIVES AND CELL BINDING MOLECULES AND METHODS OF MAKING | TEK, TEKT1, EPCAM | NOD1 2532/4885MMP2 3071/4885MMP9 3462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.