Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 7/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493223 | 1.00 | CHRM2 (0.37) | CHRM2CHRM1CHRM3RORCNR1H2 | |
| SCHEMBL875047 | 0.86 | CHRM2 (0.36) | CHRM2CHRM1CHRM3RORCNR1H2 | |
| SCHEMBL2119472 | 0.86 | CHRM2 (0.36) | CHRM2CHRM1CHRM3RORCNR1H2 | |
| SCHEMBL8990002 | 0.79 | NR1H2 (0.36) | CHRM2CHRM1CHRM3RORCNR1H2 | |
| SCHEMBL29519744 | 0.75 | CHRM2 (0.41) | CHRM2CHRM1CHRM3GPR119DDB1 | |
| SCHEMBL28735688 | 0.75 | CHRM2 (0.41) | CHRM2CHRM1CHRM3GPR119DDB1 | |
| SCHEMBL6488112 | 0.74 | EPHX1 (0.35) | CHRM2CHRM1CHRM3RORCNR1H2 | |
| SCHEMBL31386766 | 0.73 | BUB1 (0.34) | CHRM2CHRM1CHRM3RORCNR1H2 | |
| SCHEMBL2593873 | 0.73 | USP2 (0.32) | CHRM2CHRM1CHRM3RORCNR1H2 | |
| SCHEMBL25347682 | 0.72 | CHRM2 (0.37) | CHRM2CHRM1CHRM3GPR119DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030499-B2 | 1,3-dihydro-2H-indole-2-one compound and pyrrolidine-2-one compound fused with aromatic heterocycle | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |