Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21215959 | 0.83 | KDM4E (0.37) | CTSKSLC6A3MAPK1NPSR1KDM4E | |
| SCHEMBL21197694 | 0.82 | MAPK1 (0.36) | CTSKSLC6A3MAPK1NPSR1KDM4E | |
| SCHEMBL21602032 | 0.81 | PKM (0.37) | CTSKSLC6A3MAPK1NPSR1KDM4E | |
| SCHEMBL19031974 | 0.74 | ALOX5AP (0.41) | CTSKSLC6A3MAPK1NPSR1KDM4E | |
| SCHEMBL21216015 | 0.73 | MAPK1 (0.36) | CTSKSLC6A3MAPK1NPSR1KDM4E | |
| SCHEMBL24983187 | 0.72 | SLC1A3 (0.41) | CTSKALDH1A1 | |
| Lithium Ion SCHEMBL21197693 | 0.72 | MAPK1 (0.35) | CTSKSLC6A3MAPK1NPSR1KDM4E | |
| SCHEMBL3901063 | 0.71 | SLC6A3 (0.37) | SLC6A3MAPK1NPSR1KDM4EKDM4C | |
| SCHEMBL21602322 | 0.71 | TDP1 (0.38) | CTSKSLC6A3NT5ESLC6A2SLC6A4 | |
| SCHEMBL27997582 | 0.70 | MAPK1 (0.36) | CTSKSLC6A3MAPK1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022922-A1 | ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF | ANTENGENE THERAPEUTICS LIMITED (CN) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230022922-A1 | ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF | NT5E, ENTPD5, NT5C2 | CTSK 361/4885SLC6A3 373/4885MAPK1 4119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.