Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | BAX | Q07812 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13169409 | 0.85 | TSHR (0.39) | TSHRMAOA | |
| SCHEMBL3683423 | 0.80 | TSHR (0.46) | TSHR | |
| SCHEMBL751190 | 0.74 | LTA4H (0.61) | LTA4HTSHRFFAR1SRD5A2NR1H2 | |
| SCHEMBL8690058 | 0.73 | LTA4H (0.55) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL23098203 | 0.73 | SRD5A2 (0.70) | LTA4HTSHRFFAR1SRD5A2NR1H2 | |
| SCHEMBL19322270 | 0.73 | LTA4H (0.67) | LTA4HTSHRFFAR1SRD5A2NR1H2 | |
| SCHEMBL9906839 | 0.73 | SRD5A2 (0.70) | LTA4HTSHRFFAR1SRD5A2NR1H2 | |
| SCHEMBL3893562 | 0.72 | LTA4H (0.92) | LTA4HTSHRSRD5A2NR1H2BAX | |
| SCHEMBL22129853 | 0.72 | LTA4H (0.92) | LTA4HTSHRSRD5A2NR1H2BAX | |
| SCHEMBL122719 | 0.72 | LTA4H (0.92) | LTA4HTSHRSRD5A2NR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637627-B2 | Phenoxyphenyl polysiloxane composition and method for making and using same | ROHM AND HAAS COMPANY (US) | 2014-01-28 | — | — | US | disclosed |
| US-8029904-B2 | Aryl (thio)ether aryl polysiloxane composition and methods for making and using same | ROHM AND HAAS COMPANY (US) | 2011-10-04 | — | — | US | disclosed |
| EP-1927636-B1 | Aryl(thio)ether aryl polysiloxane composition and methods for making and using same | ROHM & HAAS (US) | 2010-02-10 | — | — | EP | disclosed |
| US-20090146324-A1 | Phenoxyphenyl polysiloxane composition and method for making and using same | ROHM AND HAAS COMPANY (US) | 2009-06-11 | — | — | US | disclosed |
| US-20080160323-A1 | Hydrosilation catalysts; for encapsulating semiconductors | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2008-07-03 | — | — | US | disclosed |
| EP-1927636-A1 | Aryl(thio)ether aryl polysiloxane composition and methods for making and using same | Rohm and Haas Company (US) | 2008-06-04 | — | — | EP | disclosed |