Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3683423 | 0.94 | TSHR (0.46) | TSHRALDH1A1TRPA1CALM1TDP1 | |
| SCHEMBL2498577 | 0.85 | LTA4H (0.53) | TSHRMAOA | |
| SCHEMBL8992255 | 0.83 | CYP2C9 (0.34) | — | |
| SCHEMBL13169410 | 0.82 | TSHR (0.40) | TSHRALDH1A1TRPA1CALM1TDP1 | |
| SCHEMBL23701321 | 0.74 | — | — | |
| SCHEMBL9510289 | 0.74 | — | — | |
| SCHEMBL23071707 | 0.74 | TAAR1 (0.46) | ALDH1A1MAOBIDO1TAAR1TP53 | |
| SCHEMBL13169411 | 0.74 | MAOB (0.41) | ALDH1A1TDP1MAOBMAOATAAR1 | |
| SCHEMBL311787 | 0.69 | — | — | |
| SCHEMBL23701274 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799846-B2 | Dental composition containing an epoxy functional carbosilane compound | 3M ESPE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | 3M DEUTSCHLAND GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | EPX, TAS2R41, TAS1R1 | TSHR 605/4885ALDH1A1 1405/4885TRPA1 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.