Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 3/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | CTSC | P53634 | 4/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2574911 | 0.97 | CTRB1 (0.50) | CTRB1OPRD1OPRM1OPRK1CTSC | |
| SCHEMBL2574907 | 0.97 | CTRB1 (0.50) | CTRB1OPRD1OPRM1OPRK1CTSC | |
| SCHEMBL4086489 | 0.87 | OPRD1 (0.46) | CTRB1OPRD1OPRM1OPRK1CTSC | |
| SCHEMBL27602044 | 0.84 | CTRB1 (0.61) | CTRB1CTSC | |
| SCHEMBL9143156 | 0.84 | CTRB1 (0.61) | CTRB1CTSC | |
| SCHEMBL7316156 | 0.84 | CTRB1 (0.61) | CTRB1CTSC | |
| SCHEMBL7316163 | 0.84 | CTRB1 (0.61) | CTRB1CTSC | |
| SCHEMBL11863650 | 0.83 | CTSC (0.62) | CTSCTERT | |
| SCHEMBL11863638 | 0.83 | CTSC (0.62) | CTSCTERT | |
| SCHEMBL18515816 | 0.81 | OPRD1 (0.57) | CTRB1OPRD1OPRM1OPRK1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374797-A1 | Benzazepine derivatives useful as vasopressin antagonists | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-10-12 | — | — | EP | disclosed |