Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24988223 | 0.87 | LMNA (0.42) | LMNASMN1; SMN2GAAKDM4EGRN | |
| SCHEMBL20745023 | 0.80 | KDM4E (0.42) | KDM4EGRNSORT1 | |
| SCHEMBL11982018 | 0.76 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2GAAKDM4EGRN | |
| SCHEMBL13982847 | 0.76 | LMNA (0.40) | LMNASMN1; SMN2GAAKDM4EGRN | |
| SCHEMBL27637077 | 0.70 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2GAAKDM4EGRN | |
| SCHEMBL334463 | 0.68 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2GAAKDM4EGRN | |
| SCHEMBL286931 | 0.68 | KDM4E (0.58) | LMNASMN1; SMN2GAAKDM4EGRN | |
| SCHEMBL19818707 | 0.68 | KDM4E (0.44) | LMNASMN1; SMN2GAAKDM4EGRN | |
| SCHEMBL20763628 | 0.68 | KDM4E (0.45) | KDM4EGRNSORT1 | |
| SCHEMBL24533846 | 0.67 | JAK2 (0.52) | LMNASMN1; SMN2GAACACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668866-B1 | PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2023-01-18 | — | — | EP | disclosed |