SCHEMBL24989771

SCHEMBL24989771

N=C(N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)CC2CCCC2)CCC(=O)NCCCCNC1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 1/20 0.45
▸ TSLP Q969D9 4/20 0.44
▸ SIRT2 Q8IXJ6 3/20 0.41
▸ SIRT1 Q96EB6 3/20 0.41
▸ SIRT3 Q9NTG7 3/20 0.41
▸ MC4R P32245 3/20 0.40
▸ MC5R P33032 3/20 0.40
▸ MC3R P41968 3/20 0.40
▸ MC1R Q01726 3/20 0.40
▸ ACE P12821 2/20 0.40
▸ ACE2 Q9BYF1 2/20 0.40
▸ PLK1 P53350 1/20 0.39
▸ FCGRT P55899 1/20 0.39
▸ PLG P00747 1/20 0.39
▸ KRAS P01116 1/20 0.38
▸ TUBB4A P04350 1/20 0.38
▸ TUBB P07437 1/20 0.38
▸ TUBA3C P0DPH7 1/20 0.38
▸ TUBA1B P68363 1/20 0.38
▸ TUBA4A P68366 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24990207 0.98 TSLP (0.44) FURINTSLPSIRT2SIRT1SIRT3
SCHEMBL24991502 0.92 FURIN (0.44) FURINTSLPSIRT2SIRT1SIRT3
SCHEMBL24991019 0.91 TSLP (0.48) FURINTSLPSIRT2SIRT1SIRT3
SCHEMBL24991154 0.90 TSLP (0.44) FURINTSLPSIRT2SIRT1SIRT3
SCHEMBL24990017 0.90 TSLP (0.44) FURINTSLPSIRT2SIRT1SIRT3
SCHEMBL23750072 0.90 FURIN (0.48) FURINTSLPSIRT2SIRT1SIRT3
SCHEMBL24991137 0.89 TSLP (0.43) FURINTSLPSIRT2SIRT1SIRT3
SCHEMBL23750095 0.89 TSLP (0.49) TSLPMC4RMC5RMC3RMC1R
SCHEMBL23750043 0.87 TSLP (0.45) FURINTSLPMC4RMC5RMC3R
SCHEMBL24991116 0.87 TSLP (0.44) FURINTSLPMC4RMC5RMC3R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications PALATIN TECHNOLOGIES, INC. (US) 2023-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications MC1R, MC3R, MC5R FURIN 803/4885TSLP 135/4885SIRT2 2511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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