SCHEMBL24990207

SCHEMBL24990207

N=C(N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)CC2CCCC2)CCC(=O)NCCNC1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSLP Q969D9 5/20 0.44
▸ FURIN P09958 1/20 0.43
▸ MC4R P32245 6/20 0.40
▸ MC5R P33032 6/20 0.40
▸ MC3R P41968 6/20 0.40
▸ MC1R Q01726 6/20 0.40
▸ ACE P12821 2/20 0.40
▸ ACE2 Q9BYF1 2/20 0.40
▸ SIRT2 Q8IXJ6 2/20 0.39
▸ SIRT1 Q96EB6 2/20 0.39
▸ SIRT3 Q9NTG7 2/20 0.39
▸ PLG P00747 1/20 0.39
▸ TUBB4A P04350 1/20 0.39
▸ TUBB P07437 1/20 0.39
▸ TUBA3C P0DPH7 1/20 0.39
▸ TUBA1B P68363 1/20 0.39
▸ TUBA4A P68366 1/20 0.39
▸ TUBB4B P68371 1/20 0.39
▸ TUBB3 Q13509 1/20 0.39
▸ TUBB2A Q13885 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24989771 0.98 FURIN (0.45) TSLPFURINMC4RMC5RMC3R
SCHEMBL24991137 0.91 TSLP (0.43) TSLPFURINMC4RMC5RMC3R
SCHEMBL24991502 0.90 FURIN (0.44) TSLPFURINMC4RMC5RMC3R
SCHEMBL23750043 0.89 TSLP (0.45) TSLPFURINMC4RMC5RMC3R
SCHEMBL24991019 0.89 TSLP (0.48) TSLPFURINMC4RSIRT2SIRT1
SCHEMBL24991116 0.89 TSLP (0.44) TSLPFURINMC4RMC5RMC3R
SCHEMBL24991154 0.88 TSLP (0.44) TSLPFURINMC4RMC5RMC3R
SCHEMBL23750072 0.88 FURIN (0.48) TSLPFURINMC4RMC5RMC3R
SCHEMBL24990017 0.88 TSLP (0.44) TSLPFURINMC4RMC5RMC3R
SCHEMBL23750095 0.87 TSLP (0.49) TSLPMC4RMC5RMC3RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications PALATIN TECHNOLOGIES, INC. (US) 2023-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications MC1R, MC3R, MC5R TSLP 135/4885FURIN 803/4885MC4R 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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