SCHEMBL24992152

SCHEMBL24992152

C=c1ccc(=C)n1-c1ccc(OC)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
MAPT P10636 2/20 0.48
LMNA P02545 2/20 0.48
NPC1 O15118 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
GSK3A P49840 1/20 0.46
GSK3B P49841 1/20 0.46
MGLL Q99685 1/20 0.45
POLB P06746 1/20 0.44
ATM Q13315 1/20 0.43
HTT P42858 1/20 0.42
HTR3E A5X5Y0 1/20 0.42
HTR3B O95264 1/20 0.42
ADRB1 P08588 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9389184 0.74 GSK3A (0.61) CA12CA1CA2CA7CA9
SCHEMBL8924910 0.74 NPC1 (0.53) CA12CA1CA2CA7CA9
1,4-Dimethoxybenzene SCHEMBL8489 0.71 CA1 (1.00) CA12CA1CA2CA7CA9
1,4-Dimethoxybenzene SCHEMBL21802643 0.71 CA1 (1.00) CA12CA1CA2CA7CA9
SCHEMBL6241021 0.70 HPGD (0.56) CA12CA1CA2CA7CA9
SCHEMBL9472940 0.70 ATM (0.57) CA12CA1CA2CA7CA9
SCHEMBL23642990 0.70 GSK3A (0.61) CA12CA1CA2CA7CA9
SCHEMBL17735499 0.70 NPC1 (0.62) CA12CA1CA2CA7CA9
SCHEMBL14873719 0.69 CA1 (0.58) CA12CA1CA2CA7CA9
SCHEMBL12639215 0.68 LMNA (0.73) CA12CA1CA2CA9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4130097-A1 RESIN, RESIN PRECURSOR COMPOSITION, COATING COMPOSITION, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MOLDED ARTICLE, ELECTRONIC DEVICE, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PRODUCTION METHOD Idemitsu Kosan Co., Ltd (JP) 2023-02-08 EP disclosed