Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.57 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.51 |
| ▸ | INSR | P06213 | 2/20 | 0.51 |
| ▸ | IGF1R | P08069 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | ROS1 | P08922 | 1/20 | 0.47 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24992306 | 0.90 | EGFR (0.54) | EGFRALKINSRIGF1RMET | |
| SCHEMBL27075983 | 0.89 | EGFR (0.58) | EGFRZAP70ALKINSRIGF1R | |
| SCHEMBL30015267 | 0.89 | EGFR (0.58) | EGFRZAP70ALKINSRIGF1R | |
| SCHEMBL24992447 | 0.88 | EGFR (0.69) | EGFRAURKAROS1MET | |
| SCHEMBL24992457 | 0.88 | EGFR (0.58) | EGFRALKINSRIGF1RAURKA | |
| SCHEMBL24993148 | 0.88 | EGFR (0.61) | EGFRZAP70ALKINSRIGF1R | |
| SCHEMBL24992456 | 0.88 | EGFR (0.58) | EGFRAURKAROS1MET | |
| SCHEMBL26379427 | 0.86 | EGFR (0.67) | EGFRZAP70ALKINSRIGF1R | |
| SCHEMBL24993179 | 0.83 | EGFR (0.55) | EGFRAURKAROS1MET | |
| SCHEMBL26379415 | 0.82 | EGFR (0.69) | EGFRALKINSRIGF1RAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |