Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 13/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24992039 | 0.94 | FGFR1 (0.44) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL24992183 | 0.93 | CYP3A4 (0.48) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL25589621 | 0.91 | FGFR1 (0.40) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL24992127 | 0.90 | FGFR4 (0.39) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL24992107 | 0.90 | FGFR1 (0.59) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL25589611 | 0.90 | CYP3A4 (0.38) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL25589612 | 0.89 | CYP3A4 (0.37) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL25589944 | 0.89 | FGFR1 (0.55) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL25589613 | 0.88 | FGFR1 (0.37) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL25597865 | 0.88 | CYP3A4 (0.36) | FGFR1FGFR4FGFR2FGFR3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011581-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2023-02-09 | — | — | WO | disclosed |