Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 4/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25589712 | 0.91 | CYP3A4 (0.36) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL25589611 | 0.88 | CYP3A4 (0.38) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL25589612 | 0.88 | CYP3A4 (0.37) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL24992127 | 0.88 | FGFR4 (0.39) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL24992665 | 0.88 | FGFR1 (0.49) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL24992039 | 0.87 | FGFR1 (0.44) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL25589613 | 0.87 | FGFR1 (0.37) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL25590359 | 0.86 | CYP3A4 (0.34) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL25589621 | 0.84 | FGFR1 (0.40) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL25589718 | 0.84 | CYP3A4 (0.32) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078413-A1 | FGFR2 INHIBITOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 微境生物医药科技(上海)有限公司 | 2023-05-11 | — | — | WO | disclosed |