Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997921 | 0.92 | KMT2A (0.35) | KDM4ELMNAMEN1KMT2AHPGD | |
| SCHEMBL5996433 | 0.91 | KDM4E (0.37) | KDM4ELMNAMEN1KMT2AHPGD | |
| SCHEMBL5994805 | 0.88 | ALDH1A1 (0.35) | KMT2AL3MBTL1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5996310 | 0.87 | KMT2A (0.41) | LMNAMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL5996153 | 0.87 | KMT2A (0.35) | KDM4ELMNAMEN1KMT2AHPGD | |
| SCHEMBL6403712 | 0.84 | HTR1D (0.34) | KDM4EHPGDL3MBTL1ALDH1A1MAPT | |
| SCHEMBL5994591 | 0.84 | CYP3A4 (0.39) | KDM4ELMNAMEN1KMT2AHPGD | |
| SCHEMBL152304 | 0.81 | L3MBTL1 (0.36) | LMNAMEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL6454376 | 0.81 | HPGD (0.36) | KDM4ELMNAMEN1KMT2AHPGD | |
| SCHEMBL4371155 | 0.80 | HPGD (0.33) | KDM4ELMNAMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852134-B1 | ORTHOPEDIC PHOTO-CURABLE FIXING MATERIAL | ALCARE CO LTD (JP) | 2015-04-01 | — | — | EP | disclosed |
| EP-2105452-B1 | AQUEOUS URETHANE RESIN COMPOSITION | MITSUI CHEMICALS INC (JP) | 2013-03-20 | — | — | EP | disclosed |
| US-8030227-B2 | Photocurable fixture for orthopedic surgery | ALCARE CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| US-20090264551-A1 | Photocurable fixture for orthopedic surgery background of the invention | ALCARE CO., LTD. | 2009-10-22 | — | — | US | disclosed |
| EP-2105452-A1 | AQUEOUS URETHANE RESIN COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2009-09-30 | — | — | EP | disclosed |
| US-20080045622-A1 | Photocurable Fixture for Orthopedic Surgery | ALCARE CO., LTD. (JP) | 2008-02-21 | — | — | US | disclosed |
| EP-1852134-A1 | ORTHOPEDIC PHOTO-CURABLE FIXING MATERIAL | Alcare Co., Ltd. (JP) | 2007-11-07 | — | — | EP | disclosed |
| US-7214830-B2 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-05-08 | — | — | US | disclosed |
| US-7094931-B2 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-08-22 | — | — | US | disclosed |
| EP-1135399-B2 | PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES | CIBA SC HOLDING AG (CH) | 2006-08-09 | — | — | EP | disclosed |
| US-20040248855-A1 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | IGM GROUP B.V. (NL) | 2004-12-09 | — | — | US | disclosed |
| EP-0874012-B1 | Coating composition for optical fiber | MITSUI TAKEDA CHEMICALS INC (JP) | 2004-03-10 | — | — | EP | disclosed |
| EP-1135399-B1 | PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES | CIBA SC HOLDING AG (CH) | 2002-08-07 | — | — | EP | disclosed |
| EP-1135399-A1 | PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES | Ciba SC Holding AG (CH) | 2001-09-26 | — | — | EP | disclosed |
| US-6075065-A | COMPRISES A POLYURETHANE (METH)ACRYLATE OLIGOMER, AN ETHYLENICALLY UNSATURATED COMPOUND, A BISACYLPHOSPHINE OXIDE-SERIES PHOTOPOLYMERIZATION INITIATOR, AND A TERTIARY AMINE AND NO TIN COMPONENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-06-13 | — | — | US | disclosed |
| WO-2000032612-A1 | PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-06-08 | — | — | WO | disclosed |
| US-6057034-A | COMPRISING A POLYURETHANE (METH)ACRYLATE OLIGOMER MADE FORM A POLYISOCYANATE, POLYOL, AND HYDROXY-CONTAINING ACRYLATE; AN ETHYLENICALLY UNSATURATED MONOMER, AND PHOTOPOLYMERIZATION INITIATOR; LOW VISCOSITY FOR RAPID FIBER-DRAWING | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0874012-A1 | Coating composition for optical fiber | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |
| EP-0849296-A2 | A photocurable resin composition and a method for producing the same | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-24 | — | — | EP | disclosed |
| US-5534559-A | UNSATURATED POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248855-A1 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | AGPS, PHOSPHO1, AGPAT2 | KDM4E 3169/4885LMNA 2186/4885MEN1 1567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.