Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24992324 | 0.92 | BRD4 (0.42) | BRD4EGFRFLT3BTKPAK1 | |
| SCHEMBL24993060 | 0.91 | EGFR (0.47) | BRD4EGFR | |
| SCHEMBL24993668 | 0.88 | EGFR (0.51) | EGFRBTK | |
| SCHEMBL24993654 | 0.88 | BRD4 (0.42) | BRD4EGFRFLT3BTKWEE1 | |
| SCHEMBL24993182 | 0.86 | EGFR (0.41) | BRD4EGFRFLT3BTKWEE1 | |
| SCHEMBL24992287 | 0.85 | CSF1R (0.40) | BRD4EGFRCSF1RCDK4CDK6 | |
| SCHEMBL24993046 | 0.83 | FLT3 (0.48) | BRD4EGFRCSF1RCDK4CDK6 | |
| SCHEMBL24993663 | 0.83 | EGFR (0.48) | BRD4EGFR | |
| SCHEMBL24992458 | 0.83 | BRD4 (0.54) | BRD4EGFR | |
| SCHEMBL24993669 | 0.82 | BRD4 (0.41) | BRD4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |