Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 9/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24993371 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPTCNR1SCN2ASCN10A | |
| SCHEMBL24994714 | 0.86 | NPC1 (0.46) | ALDH1A1MAPTCNR1SCN2ASCN10A | |
| SCHEMBL24993372 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTCNR1SCN2ASCN10A | |
| SCHEMBL24993339 | 0.85 | MAPT (0.52) | ALDH1A1MAPTCNR1SCN2ASCN10A | |
| SCHEMBL24993368 | 0.82 | MAPT (0.49) | ALDH1A1MAPTCNR1SCN2ASCN10A | |
| SCHEMBL24993560 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTSCN2ASCN10APOLB | |
| SCHEMBL24993306 | 0.77 | SCN10A (0.69) | ALDH1A1MAPTSCN2ASCN10APOLB | |
| SCHEMBL25003805 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPTSCN2ASCN10APOLB | |
| SCHEMBL24994723 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTCNR1POLBNPC1 | |
| SCHEMBL25003126 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010191-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |