Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25003134 | 0.90 | NPC1 (0.51) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL25003794 | 0.90 | PLK1 (0.49) | ALDH1A1KMT2AMEN1MAPTPLK1 | |
| SCHEMBL25003826 | 0.88 | CA1 (0.54) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL25002930 | 0.85 | RAB9A (0.49) | ALDH1A1KMT2AMAPTADORA3PLK1 | |
| SCHEMBL25003142 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL25003153 | 0.82 | KMT2A (0.48) | KMT2AMEN1ADORA3NPC1RAB9A | |
| SCHEMBL25003137 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTPLK1LMNA | |
| SCHEMBL25003131 | 0.80 | MAP4K4 (0.55) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL25003827 | 0.79 | FDPS (0.46) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL25003805 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTADORA3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010192-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |