Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24993525 | 0.84 | DRD2 (0.40) | PTPN11ALDH1A1HRH3DRD2SIGMAR1 | |
| SCHEMBL31015413 | 0.83 | AOC3 (0.42) | — | |
| SCHEMBL24993369 | 0.82 | AOC3 (0.43) | MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24993366 | 0.80 | AOC3 (0.45) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24993358 | 0.77 | KIF18A (0.43) | — | |
| SCHEMBL24994261 | 0.75 | KMT2A (0.41) | MAPTALDH1A1SMN1; SMN2RAD52MAPK1 | |
| SCHEMBL24993374 | 0.73 | TARDBP (0.44) | — | |
| SCHEMBL24993361 | 0.71 | SCN10A (0.41) | — | |
| SCHEMBL31078509 | 0.70 | PIM2 (0.47) | PARP1ALDH1A1 | |
| SCHEMBL24694730 | 0.69 | OGA (0.37) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010191-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |