SCHEMBL2499345

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL2493252	0.98	HTR2C (0.46)	HTR2CHTR2AHTR2BPNMTKDM1A
	SCHEMBL31758538	0.90	HTR2C (0.55)	HTR2CHTR2AHTR2BPNMTKDM1A
	SCHEMBL2496848	0.89	HTR2A (0.55)	HTR2CHTR2AHTR2BPNMTKDM1A
	Hydrochloric Acid SCHEMBL2492938	0.87	HTR2A (0.54)	HTR2CHTR2AHTR2BPNMTKDM1A
	SCHEMBL12190383	0.81	HTR2A (0.39)	HTR2CHTR2AHTR2BKDM1ASRD5A1
	SCHEMBL2498088	0.81	PNMT (0.45)	HTR2CHTR2AHTR2BPNMTKDM1A
	Hydrochloric Acid SCHEMBL2497611	0.79	HTR2A (0.38)	HTR2CHTR2AHTR2BKDM1ASRD5A1
	SCHEMBL25358373	0.78	HTR2C (0.52)	HTR2CHTR2AHTR2BPNMTKDM1A
	SCHEMBL1222048	0.76	HTR2A (0.61)	HTR2CHTR2AKDM1ASIGMAR1CRBN
	SCHEMBL28549228	0.75	DRD2 (0.41)	HTR2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.