Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 2/20 | 0.32 |
| ▸ | STS | P08842 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | TGM1 | P22735 | 1/20 | 0.31 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23707238 | 0.94 | MEN1 (0.33) | MEN1KMT2AALDH1A1NPC1MAPT | |
| SCHEMBL24993496 | 0.91 | HDAC1 (0.34) | MEN1KMT2AALDH1A1NPC1MAPT | |
| SCHEMBL23107418 | 0.82 | POLB (0.35) | MEN1KMT2AALDH1A1NPC1MAPT | |
| SCHEMBL31303368 | 0.81 | BUB1 (0.36) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL29736458 | 0.81 | HDAC1 (0.36) | MEN1KMT2AMAPK1HDAC1HDAC6 | |
| SCHEMBL23090018 | 0.81 | BUB1 (0.36) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL23089773 | 0.81 | HDAC1 (0.36) | MEN1KMT2AMAPK1HDAC1HDAC6 | |
| SCHEMBL25147504 | 0.77 | NAMPT (0.42) | MEN1KMT2ANPC1MAPTHTT | |
| SCHEMBL23089544 | 0.77 | LMNA (0.38) | ALDH1A1MAPTMAPK1HTTHDAC1 | |
| SCHEMBL23090067 | 0.76 | UCHL1 (0.36) | MEN1KMT2AHDAC1HDAC6BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023015199-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |