SCHEMBL2499549

SCHEMBL2499549

C=Cc1cccc([Si](OC(C)(C)C)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2504306 0.85 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL2502697 0.84 TP53 (0.41) TP53TDP1ALDH1A1TSHRPTGS2
SCHEMBL2504327 0.82 TP53 (0.37) TP53TDP1ALDH1A1TSHR
SCHEMBL2502583 0.81 TP53 (0.38) TP53TDP1ALDH1A1TSHRPTGS2
SCHEMBL704060 0.79 MAPK1 (0.37) TDP1ALDH1A1TSHR
SCHEMBL703641 0.77 ESR1 (0.37) TDP1ALDH1A1TSHR
SCHEMBL2497773 0.76 TP53 (0.34) TP53TDP1ALDH1A1TSHR
SCHEMBL2500418 0.74 TSHR (0.35) TP53TDP1ALDH1A1TSHR
SCHEMBL7133950 0.72 ALDH1A1 (0.43) TP53TDP1ALDH1A1TSHR
SCHEMBL2498900 0.72 ALDH1A1 (0.43) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8497334-B2 Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-30 US disclosed
US-20110245407-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-06 US disclosed