Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24249167 | 0.83 | MAPK1 (0.44) | KMT2AL3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL19728174 | 0.76 | CHRM2 (0.63) | KMT2AL3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL28411457 | 0.76 | CHRM2 (0.63) | KMT2AL3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL25888649 | 0.76 | CHRM2 (0.63) | KMT2AL3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL8185274 | 0.76 | CHRM2 (0.63) | KMT2AL3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL19728173 | 0.76 | CHRM2 (0.63) | KMT2AL3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL17593204 | 0.76 | CHRM2 (0.63) | KMT2AL3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL5480653 | 0.76 | PLA2G10 (0.40) | KMT2AL3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL22054254 | 0.76 | CHRM2 (0.63) | KMT2AL3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL24455951 | 0.76 | CACNA1H (0.36) | ALDH1A1CACNA1HHPGDOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043863-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043863-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | WEE2, WEE1, RORB | KMT2A 2361/4885L3MBTL1 4229/4885CHRM2 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.