Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12113770 | 0.77 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2HTTADORA3ADORA2A | |
| SCHEMBL16975637 | 0.77 | HTT (0.42) | ALDH1A1SMN1; SMN2HTTADORA3ADORA2A | |
| SCHEMBL11617352 | 0.76 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HTTADORA3ADORA2A | |
| SCHEMBL24174703 | 0.76 | RET (0.47) | ALDH1A1SMN1; SMN2HTTADORA2AADORA1 | |
| SCHEMBL12711925 | 0.73 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HTR2AHTR2CPDPK1 | |
| SCHEMBL13660393 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2HTTADORA3ADORA2A | |
| SCHEMBL10226489 | 0.68 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CDK2PDPK1 | |
| SCHEMBL14132816 | 0.68 | — | — | |
| SCHEMBL25975228 | 0.68 | KDM4E (0.31) | — | |
| SCHEMBL12120587 | 0.67 | IDH1 (0.34) | ALDH1A1CYP1A2CDK2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043863-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043863-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | WEE2, WEE1, RORB | ALDH1A1 1037/4885SMN1; SMN2 4884/4885HTT 4043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.