Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2507738 | 0.91 | PPARG (0.45) | MAPTLMNAGAAPOLBKMT2A | |
| SCHEMBL2476533 | 0.90 | MAPT (0.41) | MAPTLMNAGAAPOLBKMT2A | |
| SCHEMBL2480597 | 0.89 | MAPT (0.42) | MAPTLMNAGAAPOLBKMT2A | |
| SCHEMBL2499786 | 0.89 | LMNA (0.44) | MAPTLMNAGAAPOLBKMT2A | |
| SCHEMBL2483934 | 0.89 | PPARA (0.39) | MAPTLMNAGAAPOLBKMT2A | |
| SCHEMBL2507629 | 0.86 | KMT2A (0.44) | MAPTLMNAGAAPOLBKMT2A | |
| SCHEMBL2481989 | 0.84 | PPARG (0.44) | MAPTLMNAGAAPOLBKMT2A | |
| SCHEMBL2508287 | 0.83 | KMT2A (0.42) | MAPTLMNAGAAPOLBKMT2A | |
| SCHEMBL2507379 | 0.83 | PPARG (0.45) | MAPTLMNAGAAPOLBKMT2A | |
| SCHEMBL2504726 | 0.83 | MAPT (0.46) | MAPTLMNAGAAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376423-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | Dow Global Technologies LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010078519-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |