Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2503630 | 0.92 | MAPT (0.41) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2508594 | 0.92 | PPARG (0.42) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2481989 | 0.92 | PPARG (0.44) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2508844 | 0.90 | LMNA (0.39) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2480597 | 0.89 | MAPT (0.42) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2476544 | 0.89 | LMNA (0.42) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2499657 | 0.89 | MAPT (0.42) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2499214 | 0.88 | PPARG (0.45) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2478999 | 0.87 | MAPT (0.41) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2509210 | 0.85 | TDP1 (0.42) | LMNAMAPTPOLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376423-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | Dow Global Technologies LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010078519-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |