SCHEMBL2499807

SCHEMBL2499807

[CH2]Cc1ccc(CC=C)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.54
▸ CYP3A4 P08684 3/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ TP53 P04637 1/20 0.54
▸ ALOX15 P16050 1/20 0.54
▸ TSHR P16473 1/20 0.54
▸ ALOX12 P18054 1/20 0.54
▸ XDH P47989 1/20 0.48
▸ MAPT P10636 4/20 0.46
▸ GABRA1 P14867 4/20 0.46
▸ GABRB2 P47870 4/20 0.46
▸ CNR2 P34972 4/20 0.46
▸ MEN1 O00255 3/20 0.46
▸ GAA P10253 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ PPARG P37231 2/20 0.46
▸ PPARD Q03181 2/20 0.46
▸ CNR1 P21554 2/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ ALDH2 P05091 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173301 0.88 ALDH1A1 (0.64) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Phosphine SCHEMBL28908227 0.85 ALDH1A1 (0.61) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Bromide SCHEMBL8645583 0.85 ALDH1A1 (0.61) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Water SCHEMBL29179560 0.85 ALDH1A1 (0.61) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL1717412 0.83 ALDH1A1 (0.54) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Hydrogen Peroxide SCHEMBL7816450 0.82 ALDH1A1 (0.58) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Hydrogen Peroxide SCHEMBL5496256 0.82 ALDH1A1 (0.58) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL9005966 0.81 ALDH1A1 (0.52) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL10693711 0.80 ALDH1A1 (0.56) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL584333 0.80 ALDH1A1 (0.56) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100204409-A1 Process For Crosslinking Thermoplastic Polymers With Silanes Employing Peroxide Blends, The Resulting Crosslinked Thermoplastic Polymer Composition And Articles Made Therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 — — US claimed
JP-61221171-A — — None — — JP disclosed
JP-62096469-A — — None — — JP disclosed
EP-2084217-B1 PROCESS FOR CROSSLINKING THERMOPLASTIC POLYMERS WITH SILANES EMPLOYING PEROXIDE BLENDS, THE RESULTING CROSSLINKED THERMOPLASTIC POLYMER COMPOSITION AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2020-07-22 — — EP disclosed
US-8030415-B2 Process for crosslinking thermoplastic polymers with silanes employing peroxide blends, the resulting crosslinked thermoplastic polymer composition and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2011-10-04 — — US disclosed
US-20100204409-A1 Process For Crosslinking Thermoplastic Polymers With Silanes Employing Peroxide Blends, The Resulting Crosslinked Thermoplastic Polymer Composition And Articles Made Therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 — — US disclosed
EP-2084217-A2 PROCESS FOR CROSSLINKING THERMOPLASTIC POLYMERS WITH SILANES EMPLOYING PEROXIDE BLENDS, THE RESULTING CROSSLINKED THERMOPLASTIC POLYMER COMPOSITION AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2009-08-05 — — EP disclosed
WO-2008060508-A2 PROCESS FOR CROSSLINKING THERMOPLASTIC POLYMERS WITH SILANES EMPLOYING PEROXIDE BLENDS, THE RESULTING CROSSLINKED THERMOPLASTIC POLYMER COMPOSITION AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-05-22 — — WO disclosed
US-20080114134-A1 Process for crosslinking thermoplastic polymers with silanes employing peroxide blends, the resulting crosslinked thermoplastic polymer composition and articles made therefrom GENERAL ELECTRIC COMPANY (US) 2008-05-15 — — US disclosed
JP-S6296469-A 2-PHENYLPYRIDINE DERIVATIVE SEIKO EPSON CORP 1987-05-02 — — JP disclosed
JP-S61221171-A 2-PHENYLPYRIDINE DERIVATIVE SEIKO EPSON CORP 1986-10-01 — — JP disclosed
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