Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 11/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 11/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3328 | 0.94 | LTB4R2 (0.42) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL2501 | 0.92 | LTB4R2 (0.49) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL8483304 | 0.91 | LTB4R2 (0.42) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL3148 | 0.90 | AGTR1 (0.46) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL5593137 | 0.87 | AGTR1 (0.48) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL30218406 | 0.87 | AGTR1 (0.48) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL8524526 | 0.85 | AGTR1 (0.47) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL2189 | 0.85 | AGTR1 (0.54) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL4473046 | 0.85 | AGTR1 (0.47) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL4473048 | 0.85 | AGTR1 (0.47) | LTB4R2AGTR1ABCB11GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | claimed |
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | claimed |
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |