SCHEMBL4473048

SCHEMBL4473048

CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)[C@@](OC)(C(=O)O)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 11/20 0.47
LTB4R2 Q9NPC1 11/20 0.46
ABCB11 O95342 1/20 0.46
GP6 Q9HCN6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4473046 1.00 AGTR1 (0.47) AGTR1LTB4R2ABCB11GP6
SCHEMBL30218406 0.86 AGTR1 (0.48) AGTR1LTB4R2ABCB11GP6
SCHEMBL5593137 0.86 AGTR1 (0.48) AGTR1LTB4R2ABCB11GP6
SCHEMBL2500 0.85 LTB4R2 (0.49) AGTR1LTB4R2ABCB11GP6
SCHEMBL30218387 0.85 AGTR1 (0.45) AGTR1LTB4R2ABCB11GP6
SCHEMBL2501 0.84 LTB4R2 (0.49) AGTR1LTB4R2ABCB11GP6
SCHEMBL3148 0.83 AGTR1 (0.46) AGTR1LTB4R2ABCB11GP6
SCHEMBL25964166 0.81 AGTR1 (0.58) AGTR1LTB4R2ABCB11GP6
SCHEMBL8242346 0.81 AGTR1 (0.58) AGTR1LTB4R2ABCB11GP6
SCHEMBL2635 0.80 AGTR1 (0.71) AGTR1LTB4R2ABCB11GP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090203920-A1 METHOD FOR ISOLATING 5-SUBSTITUTED TETRAZOLES SANOCHEMIA PHARMAZEUTIKA AG (AT) 2009-08-13 US disclosed
EP-1910251-A1 METHOD FOR ISOLATING 5-SUBSTITUTED TETRAZOLES Sanochemia Pharmazeutika Aktiengesellschaft (AT) 2008-04-16 EP disclosed
WO-2007014412-A1 METHOD FOR ISOLATING 5-SUBSTITUTED TETRAZOLES SANOCHEMIA PHARMAZEUTIKA AG (AT) 2007-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203920-A1 METHOD FOR ISOLATING 5-SUBSTITUTED TETRAZOLES TH, CASP5, TYR AGTR1 1702/4885LTB4R2 775/4885ABCB11 527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.