Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16840141 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2HSD11B1GAATDP1LMNA | |
| SCHEMBL16840139 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2HSD11B1GAATDP1LMNA | |
| SCHEMBL2232346 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2GAATDP1LMNAKMT2A | |
| SCHEMBL17586745 | 0.78 | SMN1; SMN2 (0.37) | SMN1; SMN2HSD11B1GAATDP1EPHX1 | |
| SCHEMBL8936212 | 0.77 | KMT2A (0.35) | SMN1; SMN2EPHX1SLC1A2SLC1A1KMT2A | |
| SCHEMBL16841467 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2HSD11B1GAATDP1LMNA | |
| SCHEMBL16841477 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2HSD11B1GAATDP1LMNA | |
| SCHEMBL13232149 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2HSD11B1GAATDP1LMNA | |
| SCHEMBL19315873 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2HSD11B1GAATDP1LMNA | |
| SCHEMBL22874962 | 0.75 | SMN1; SMN2 (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014907-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |