Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | PITRM1 | Q5JRX3 | 3/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.34 |
| ▸ | FAP | Q12884 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27561118 | 0.84 | APLNR (0.42) | KDM4EMAPTSLC1A2SLC1A1SMN1; SMN2 | |
| SCHEMBL3694371 | 0.79 | CYP2C9 (0.40) | KDM4EMAPTEPHX1SMN1; SMN2CCR2 | |
| SCHEMBL25001002 | 0.77 | SMN1; SMN2 (0.38) | KMT2AKDM4EMAPTATMCYP2D6 | |
| SCHEMBL15541347 | 0.77 | APLNR (0.41) | KMT2AKDM4EMAPTATMCYP2D6 | |
| SCHEMBL15541036 | 0.77 | APLNR (0.41) | KMT2AKDM4EMAPTATMCYP2D6 | |
| SCHEMBL28598649 | 0.77 | APLNR (0.41) | KMT2AKDM4EMAPTATMCYP2D6 | |
| Hydrochloric Acid SCHEMBL16738264 | 0.76 | APLNR (0.40) | KMT2AKDM4EMAPTATMCYP2D6 | |
| SCHEMBL29790515 | 0.74 | KDM4E (0.37) | KMT2AKDM4EMAPTATMCYP2D6 | |
| SCHEMBL15542498 | 0.73 | KDM4E (0.39) | KMT2AKDM4EMAPTATMCYP2D6 | |
| SCHEMBL10423033 | 0.72 | LTB4R (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510530-A | WHEN POLYMERIZED GIVE OPTICALLY ACTIVE POLYMERS WHICH ARE USEFUL AS ADSORBENTS FOR CHROMATOGRAPHIC SEPARATION OF RACEMATES INTO ENANTIOMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
| US-5481026-A | ADDITION POLYMERIZABLE TO CHROMATOGRAPHIC SUPPORTS FOR SEPARATION OF RACEMIC MIXTURES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-02 | — | — | US | disclosed |
| US-5432252-A | Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| US-5432251-A | Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| US-5357001-A | Optically active amino acid sulphoxide and amino acid sulphone derivatives, their preparation, their polymerisation and use as adsorbents for chromatographic resolution of racemates | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| US-5347042-A | Optically active sulphur-containing amino acid derivatives, their preparation, their polymerisation to give optically active polymers and the use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1994-09-13 | — | — | US | disclosed |