Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.55 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001598 | 0.89 | EGFR (0.55) | EGFRBTKALKMETINSR | |
| SCHEMBL25002724 | 0.85 | EGFR (0.52) | EGFRBTKALKCDK19MET | |
| SCHEMBL29084096 | 0.84 | EGFR (0.71) | EGFRBTKALKCDK19MET | |
| SCHEMBL25001715 | 0.81 | EGFR (0.61) | EGFRBTKALKMETINSR | |
| SCHEMBL25001347 | 0.81 | EGFR (0.63) | EGFRBTKALKMETINSR | |
| SCHEMBL25820886 | 0.80 | EGFR (0.57) | EGFR | |
| SCHEMBL29974926 | 0.79 | EGFR (0.65) | EGFRBTKALKINSRIGF1R | |
| SCHEMBL29084036 | 0.78 | EGFR (0.65) | EGFRBTKALKMETINSR | |
| SCHEMBL29084045 | 0.78 | EGFR (0.67) | EGFRBTKALKINSRIGF1R | |
| SCHEMBL27091519 | 0.78 | EGFR (0.67) | EGFRBTKALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129996-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-08 | — | — | EP | disclosed |