Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.65 |
| ▸ | ALK | Q9UM73 | 8/20 | 0.63 |
| ▸ | INSR | P06213 | 6/20 | 0.63 |
| ▸ | IGF1R | P08069 | 6/20 | 0.63 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29084045 | 0.93 | EGFR (0.67) | EGFRALKINSRIGF1RPLK1 | |
| SCHEMBL29084096 | 0.89 | EGFR (0.71) | EGFRALKINSRIGF1RPLK1 | |
| SCHEMBL27091519 | 0.86 | EGFR (0.67) | EGFRALKINSRIGF1RBTK | |
| SCHEMBL29084036 | 0.86 | EGFR (0.65) | EGFRALKINSRIGF1RPLK1 | |
| SCHEMBL25001347 | 0.86 | EGFR (0.63) | EGFRALKINSRIGF1RPLK1 | |
| SCHEMBL25001715 | 0.84 | EGFR (0.61) | EGFRALKINSRIGF1RPLK1 | |
| SCHEMBL29084069 | 0.84 | EGFR (0.64) | EGFRALKINSRIGF1RPLK1 | |
| SCHEMBL29083946 | 0.83 | EGFR (0.63) | EGFRALKINSRIGF1RPLK1 | |
| SCHEMBL29974578 | 0.83 | EGFR (0.62) | EGFRBTK | |
| SCHEMBL23442001 | 0.82 | EGFR (0.69) | EGFRALKINSRIGF1RBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206797-A1 | EGFR INHIBITOR, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2022-10-06 | — | — | WO | claimed |
| WO-2022206797-A1 | EGFR INHIBITOR, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2022-10-06 | — | — | WO | disclosed |