Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436133 | 0.77 | — | — | |
| SCHEMBL25002364 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2 | |
| SCHEMBL19705223 | 0.73 | KDM4E (0.48) | KDM4ELMNACYP2C19SMN1; SMN2TSHR | |
| SCHEMBL15336677 | 0.72 | — | — | |
| SCHEMBL21557423 | 0.71 | LMNA (0.50) | KDM4ELMNACYP2C19SMN1; SMN2TSHR | |
| SCHEMBL26339129 | 0.69 | KDM4E (0.44) | KDM4ELMNACYP2C19SMN1; SMN2TSHR | |
| SCHEMBL26339041 | 0.68 | KDM4E (0.42) | KDM4ELMNACYP2C19SMN1; SMN2TSHR | |
| SCHEMBL25002627 | 0.68 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL25001423 | 0.68 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL24046707 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129996-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-08 | — | — | EP | disclosed |