Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25002627 | 0.74 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL25002839 | 0.74 | KDM4E (0.47) | SMN1; SMN2 | |
| SCHEMBL25001423 | 0.74 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL248285 | 0.72 | — | — | |
| SCHEMBL21257727 | 0.71 | OPRM1 (0.35) | SMN1; SMN2 | |
| SCHEMBL3997782 | 0.71 | ATAD2 (0.36) | SMN1; SMN2CRBNHPGD | |
| SCHEMBL6318998 | 0.71 | — | — | |
| SCHEMBL1441539 | 0.70 | — | — | |
| SCHEMBL2392698 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL31401458 | 0.68 | NEK2 (0.35) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129996-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-08 | — | — | EP | disclosed |