Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25003808 | 0.84 | ABCB1 (0.48) | ABCB1POLBKMT2AMAPTMEN1 | |
| SCHEMBL4943612 | 0.84 | ALDH1A1 (0.57) | POLBKMT2AMAPTMEN1CYP1A2 | |
| SCHEMBL4943742 | 0.79 | HTT (0.51) | KMT2AMAPTMEN1CYP1A2CYP2C19 | |
| SCHEMBL21981938 | 0.78 | HTT (0.67) | POLBKMT2AMAPTMEN1CYP1A2 | |
| SCHEMBL1143497 | 0.78 | ALDH1A1 (0.50) | POLBKMT2AMAPTMEN1CYP1A2 | |
| SCHEMBL22066403 | 0.78 | HPGD (0.56) | KMT2AMAPTMEN1CYP1A2CYP2C19 | |
| SCHEMBL4946307 | 0.78 | LMNA (0.57) | POLBKMT2AMAPTMEN1CYP1A2 | |
| SCHEMBL25002899 | 0.78 | ALDH1A1 (0.65) | MAPTSCN10AERCC5FEN1ALDH1A1 | |
| SCHEMBL3059132 | 0.77 | ALDH1A1 (0.62) | POLBKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL26263255 | 0.77 | SUCNR1 (0.64) | ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010192-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |